Cleanroom kit for pharma powder densification
The Pharmapaktor is widely used in the phrmaceutical field for pre-densification of active ingredient mixes prior to final tabletting and capsule filling operations and the new Series C is designed specifically to meet all exacting qualification and validation requirements, as well as cleanroom requirements.
The press agglomeration principle of the Pharmapaktor produces a compacted product, the shape of which is determined by the roll surface – smooth surfaces producing flakes and fluted ones, granules.
Horizontal feed screws dose the material into a vertical pre-densification screw from which the actual controlled feed to the compacting rolls takes place. Vacuum de-aeration is applied to the nip area of the rolls in order to achieve a higher efficiency and reduce the amount of fines. The exhaust air system is equipped with a HEPA filter.
To protect heat sensitive materials the compacting rolls and cheek plates are both cooled.
Final flake crushing is incorporated in an efficient, gentle, two-stage process where the speed and rotation angle are adjustable. Different rotor types combined with different mesh types produce consistent granular materials to suit individual specifications.
Accessories such as drives, electric cabinet, cooling water supply and vacuum pump are located at the rear and are hygienically covered in a dust tight enclosure.
The product area is encapsulated in a negative pressure environment. A safety glass door with double lip seal ensures good accessibility. During operation, the containment level is supervised by a limit switch.
A Pharmapaktor built to a special ‘through the wall’ design is available, with all mechanical and electrical services out of the cleanroom area to facilitate maintenance and ensure product integrity.
The Pharmapaktor Series C is available in three sizes and is available in single units or as part of a system incorporating vacuum transport, screening and flake crushing.