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Market Reports
Cleanroom tightness and room pressurisation: Discrepancy?
A cascaded room-pressure regime has been considered for decades to prevent cross-contamination of different processes. But Harald Flechl from ISPE says today's tight cleanrooms must have leaks to ensure a room-pressure regulation - so why should we build tight cleanrooms?
Milos Perovic | Termovent
In an interview with Cleanroom Technology, HVAC specialist COO and Head of the Cleanroom division was proud to discuss the behind-the-scenes importance of controlled environments during a time of pandemic
The evolving role of a contamination control strategy in Annex 1
A Contamination Control Strategy is a cyclical process designed to prompt the manufacturers to identify and resolve risk. With the 2020 draft update to Annex 1, David Keen from Ecolab looks at the interesting specific impacts of the changes on the role of a well-designed CCS
Adoption of rapid methods for QC microbiology in biopharmaceuticals
Rapid turnaround times and high sensitivity are essential for microbial QC testing. David Jones from Rapid Micro Biosystems explains that by the time a traditional test is completed, it can be difficult to rewind several days into the past and pinpoint the cause of a contamination event
The benefits of decentralised air handling
Performance requirements and sustainability targets can sometimes be at odds in the cleanroom world, but decentralised air handling system design can actually benefit both says Connect 2 Cleanrooms' Sam Armer
Cleanroom Conference and Manufacturing Chemist Live events set to go ahead
The co-located events will go ahead in October with new safety measures in place, after being postponed from their original date at the start of summer due to COVID-19
Nano-copper technology for antimicrobial surface design
Research has shown that copper ions are released when microbes land on a surface and can kill them, but regular copper can cause an uneven surface that is ideal for the microorganisms to adhere to. Selina Ambrose from Promethean Particles discusses nano-copper as a novel technology aiming to address this with liquid dispersion
Isolators: The beginnings of a new trend in Asia
To date, very few filling and closing machines have been installed in Asia. Aprogen Biologics and Optima Korea are both convinced that this will soon change as they install an isolator system in South Korea
Reginald Fernandes & Jamie Tempest | Reading Scientific Services
When taking its first venture into cleanroom technologies and sterility testing, RSSL picked a balanced team of microbiologists with different specialisms to guide them
UK market report: Cleanroom business from Brexit to COVID-19
Uncertainty is a word all UK operators are well-acquainted with by now, from Brexit to a global pandemic. Speaking to directors of companies in the thick of it shows how resilience and preparedness is helping them transition to the ‘new normal’
Isolator transfer design for ATMP products
A challenge posed by the increase of closed systems is the transfer of semi-finished products without losing the aseptic conditions required by regulations. A new study has tested a transfer system aiming to offer biocontainment without losing cell viability of ATMP products
Putting disinfectant to the test: Designing a field trial
Cleaning and disinfection is a process that can become very elaborate in cleanrooms. Tim Sandle in conjunction with Ecolab Life Sciences discusses designing a thorough and reliable field trial to test this process
Annex 1: How v.12 update impacts cleanroom cleaning and disinfection
The latest draft of sterile manufacturing guidelines may change again, but Matt Cokely from Ecolab says the direction of travel for the guidance is reasonably clear with regards to the guidance for cleaning and disinfection as an integral part of a Contamination Control Strategy
Contamination in a changing food production industry
The European food sector has changed significantly over the last three years. The influence equipment manufacturers have had on cross-contamination and standard cleaning requirements is key to enabling these advances
Cleaners and carrier fluids: Preventing contamination in medical device production
Modern cleaning and coating fluid technologies and associated vapour degreasing equipment provide consistent and reliable device cleaning. However, these modern cleaning fluids offer added benefits beyond this
COVID-19: Testing for surface and air presence
Protecting healthcare workers against coronavirus requires a multi-faceted approach. Rapid testing technology for aerosolised and surface virus are two ways that ensure detection for an effective management strategy
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How to design your pharmaceutical facility disinfection programme: Development, validation, and implementation
The development, validation, and implementation of a robust disinfection programme are critical components of Good Manufacturing Practices (GMP). James Polarine, Matt Hofacre and Tony Cundell explain what you need to do
Cleanroom Technology Awards 2026: The winners
The winners of the Cleanroom Technology Awards 2026 have now been revealed. The 2026 edition brought together some of the most forward-thinking organisations in the industry, recognising innovation, technical excellence, and impactful advancements across cleanroom design, operation, and technology
API production: Cleaning equipment between batches
Cleaning is an essential part of the API production and it’s important to ensure that all traces of the previous batch are removed before the start of the next one, Pat Downs, Cleaning Co-ordinator at Cambrex discusses
Annex 1: How new draft impacts cleaning and disinfection in cleanrooms
The v.12 draft update to EU GMP Annex 1 has laid out how cleaning and disinfection should be considered ‘together’ within a documented contamination control strategy
Semiconductor fab design: What do you have to consider for effective plant layout?
A well-designed layout optimises workflow, ensuring that materials and personnel move efficiently through the cleanroom. So what needs to be established to achieve this? The team at Jimmy Lea P/L discuss
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