Integrates the purification step directly in a buffer tank
GEA has added a Filter-in-Tank (FiT) system for the treatment of fermentation broths in the production of insulin to its portfolio.
The system integrates the purification step, previously a downstream process, directly in a buffer tank. This eliminates the need for the downstream filtration process and subsequent associated apparatus. A process of gentle filtration, which makes use of the hydrostatic pressure in the tank, now takes place without damaging the product while delivering optimum yield.
GEA says the FiT system sets new process standards in the pharmaceutical industry and offers a number of advantages for the user: the entire post fermentation purification is carried out in one process step using only a buffer tank; the FiT system, as one complete unit, can be hygienically cleaned (CIP) and can also be sterilised (SIP). This results in time, space and resource saving, and a sustainable production process with optimised product quality and yield.
The FiT stem exclusively uses GEA in-house components and has been developed with a leading pharmaceutical company as a pilot plant to produce a system suitable particularly for pharmaceutical industry applications, as well as those in food and biotechnology industries.