Airflow visualisation is a useful method for risk assessment of pharmaceutical processing. Dr Tim Sandle, from the Pharmaceutical Microbiology Interest Group (Pharmig), demonstrates how, using an airflow study at a filtration transfer activity in an aseptic filling facility.
Because a cleanroom is designed to control the concentration of airborne particles, a large amount of clean (filtered) air is required to remove or dilute contaminants for satisfactory operations in a critical cleanroom environment. Although this is controlled through Heating, Ventilation and Air Conditioning (HVAC) systems and assessed through the measurement of physical parameters, e.g. airflow rates, for critical operations such as aseptic filling, a visualisation of the air movement is required.1
Knowing how air moves in a cleanroom or clean air device is important to help understand how the air affects any contamination that might be present. This can be achieved through airflow visualisation studies.