Cambrex Corporation has announced the expansion project at its Mirabel, Québec site in Canada progresses well. The small molecule API manufacturer added a cGMP packaging line and a new filler on the existing packaging line. By June 2019, the monthly capacity will be 1.2 million bottles compared with approximately 600,000 per month today.
The new cGMP liquid packaging line allows the use of two fillers (XP and non-XP) working in parallel from process development through to cGMP commercial production and will now offer flexibility to accommodate ethanol and isopropanol-based solutions, aqueous solutions, lotions or suspensions. A new vision system has also been installed for online serialisation.
“This investment effectively doubles the liquid packaging capacity and weekly output at the site, while improving production cycle time and providing greater flexibility to customers,” said Maryse Laliberte, VP & General Manager, Cambrex Mirabel.
“By operating multiple liquid packaging lines that utilise the same technology, we are able to improve reaction times for our customers’ specific requirements and to support unexpected increases in demand.”
The new cGMP packaging line is linked to the existing storage tank to fill solution and suspension, and to explosion-proof ratings tanks to allow for fill solutions containing 100% alcohol or peroxide. The next-generation automatic inline, high precision filler machine will be in operation by June 2019.
Cambrex acquired the 226,000 sqft Montreal facility, formerly part of Halo Pharma, in September 2018. https://www.manufacturingchemist.com/news/article_page/Cambrex_completes_acquisition_of_Halo_Pharma/147092
The plant is dedicated to formulation development and finished dosage manufacturing services and can accommodate a wide range of solid and liquid drug product dosage forms, including suspensions and solutions, non-sterile, semi-solids, lotions, creams, ointments and suppositories.
It can also support high volume and small-batch manufacturing and offers a variety of packaging services for bottles, tubes and cartons.
