Sustainable humidification for cleanrooms: Why water quality matters

Published: 2-Jul-2025

Maintaining a consistent humidity is critical in a cleanroom, and there are some key ways humidifiers can be more sustainable for cost and environmental impact. Duncan Curd, Global Business Development Leader at DriSteem discusses

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Cleanrooms require precise environmental control, with humidity regulation playing a crucial role in maintaining product integrity, process stability, and compliance with stringent standards. 

Poor humidity control can lead to electrostatic discharge (ESD), microbial contamination, material instability, and production inefficiencies, directly impacting the pharmaceutical, semiconductor, and biotechnology industries.

For senior management, this means regulatory non-compliance risks and financial losses; for formulation and research teams, humidity fluctuations can degrade sensitive materials; for infection control, improper humidity can foster microbial growth; and for production teams, it can lead to equipment failures and inconsistent process outcomes.

Isothermal (steam) humidifiers are widely used in these environments because they provide sterile, consistent humidity levels. However, their energy-intensive operation and water consumption can present challenges in sustainability.

To select the right isothermal humidifier, it’s important to consider key factors that align with sustainability goals such as optimising water usage, minimising condensate waste, and reducing energy consumption.

What impact does supply water quality have in humidifier sustainability?

Supply water quality significantly influences the efficiency and longevity of isothermal humidifiers. Impurities such as minerals, chlorides, and particulates can cause scaling, corrosion, and frequent maintenance issues, increasing water and energy waste.

Poor water quality can also result in excessive blowdown cycles—periodic purges of water from the system to remove concentrated dissolved solids and prevent scale buildup, further contributing to water waste and energy inefficiency. Additionally, untreated or improperly treated water can introduce microbial contamination, affecting cleanroom sterility and requiring more frequent system maintenance and sanitisation.

Organisations can optimise humidifier performance and mitigate common water-related issues by including appropriate water treatment. In cleanroom environments, reverse osmosis (RO) and deionisation (DI) are often used to achieve ultrapure water.

RO removes up to 99% of dissolved solids, organic matter, and microbial contaminants through a semi-permeable membrane. At the same time, DI eliminates remaining ions using ion exchange resins, ensuring the highest level of water purity.

Here’s how water treatment systems work to improve isothermal humidifier performance:


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