West offers steam-sterilised plungers for prefillable glass syringes

Published: 3-Aug-2011
Packaging Drug Delivery Cleaning Pharmaceutical

Mitigate risk of chemical and physical deterioration of plungers


West Pharmaceutical Services, a manufacturer of systems and components for injectable drug administration, has announced a new line of steam-sterilised plungers for prefillable glass syringes.

The Westar Ready-to-Use (RU) steam-sterilised plungers can mitigate risk of chemical and physical deterioration of plungers through a steam sterilisation cycle that can minimise impact on the elastomer’s physical characteristics and on chemical oxidation and degradation during the plungers’ shelf life, the Lionville, PA, US-based firm says.

The new plungers can also decrease the number and lower the levels of extractables, with less potential for interaction between the plunger and the drug; and improve the function of the prefilled syringe due to lower and more consistent break loose forces.

The Westar RU steam sterilisation process is fully validated and supported by West’s technical and regulatory expertise.

Plungers are available from West and its long-time partner, Daikyo Seiko. They fit standard prefillable syringes and comply with US, European and Japanese pharmacopeias.

See more

You may also like

Design & Build

FOYA highlights the demand for agile cleanroom builds

Read more
Each year the Facility of the Year Awards recognise the best projects carried out in pharmaceutical builds around the globe. Highlights of those projects that involved cleanrooms and contamination control are presented here

Trending Articles

  1. You need to be a subscriber to read this article.
    Click here to find out more.
    What is ISO 8 cleanroom classification? Each cleanroom class is denoted by a maximum concentration of particles per cubic meter or cubic foot of air. ISO 8 is the second lowest cleanroom classification
  2. Syntegon launches new "Settle Plate Changer" for automated viable monitoring Syntegon has patented its new Settle Plate Changer (SPC) for automated viable monitoring in the aseptic filling process
  3. APIs: Bioreactor hoists with a multipurpose twist Peter Devenny of PalPharma describes the solution for a biotech facility in Switzerland designed to handle filled bioreactors across GMP areas to produce ten metric tons of antibody per year
  4. Sterile transfer expert ABC Transfer chooses exclusive distributor in Italy Amira has been chosen by ABC to be the exclusive distributor of ABC Transfer Rapid Transfer Port products in Italy
  5. The details of dust extraction in controlled environments To choose the right machine, the nature of the dust and the statutory regulations for its handling and removal, as well as classification of the machine and filter technology, must be considered. Daniel Took from archer reminds us, the lower the Threshold Limit Value (TLV) for dust, the higher the health risk

Upcoming event

EMPQ Essentials and Real-World Strategies for Successful Cleanroom Qualifications

16 January 2025 | Virtual See all

You may also like

Design & Build

FOYA highlights the demand for agile cleanroom builds

Each year the Facility of the Year Awards recognise the best projects carried out in pharmaceutical builds around the globe. Highlights of those projects that involved cleanrooms and contamination control are presented here
Manufacturing

West expands SmartDose manufacturing capacity at Scottsdale, Arizona

Includes cleanroom manufacturing and additional laboratory space
You need to be a subscriber to read this article.
Click here to find out more.
Manufacturing

Selecting stoppers for use in the lyophilisation of moisture-sensitive drugs

When considering the lyophilisation of moisture-sensitive biopharmaceuticals, companies must not only consider the moisture transfer via the container but also the stopper, as Dr Heike Kofler, West Pharmaceutical Services, explains
Regulatory

West’s Vial2Bag DC device receives US FDA 510(k) clearance and CE Mark

Universal needle-free reconstitution and transfer system now available for use in hospitals
Manufacturing

West Pharmaceutical Services installs Impulse conveyor in cleanroom

Sanitary electromagnetic vibratory conveyor helps West maintain the highest product quality
You need to be a subscriber to read this article.
Click here to find out more.
Packaging

Particulates in parenterals

Particulate matter is a key indicator of quality for injectable drug products. Test methods are being improved with the intent to find the materials responsible for the particle(s). The desired goal of zero defects is not a workable acceptance criterion for visible particulate matter because of current packaging components and processing capabilities. The value of vision inspection systems for elastomeric primary components is shown to mitigate the risk of particulates in finished parenteral drug products.
You need to be a subscriber to read this article.
Click here to find out more.
Packaging

Avoiding glass delamination

Contamination with glass flakes caused by delamination of the internal finish of container closure systems or prefilled syringes has caused numerous drug recalls. Surface imperfections and aggressive drug components can lead to interaction between product and container, resulting in leaching, dissolution, ion exchange and formation of precipitants or particles; use of cyclic olefin polymers as an alternative to glass can avoid these issues
Subscribe now