When carrying out R&D activities one difficulty is that the toxicity of the material being developed is often an unknown quantity and therefore the activities call for stringent requirements such as being able to control the environment in which the work is being carried out.
There could be a risk of dust explosion, cross contamination, unknown compound characteristics or toxicity to the operator. In addition, delicate tasks such as weighing microgrammes may need to be completed.
With the development of an analytical isolator, flexibility is a key factor, along with the assurance that the containment level or operator exposure is kept to a very low level. Most developmental compounds/processes will not have been assigned a toxicity level as yet and so the assumption has to be a worst case scenario.