Nottingham Trent University
Clifton Campus Clifton Lane
+44 7717 224731
Medical Technologies Innovation Facility is a state of the art facility bring together the laboratories, equipment, clean rooms and experts necessary to take innovative medical technologies from bench to bedside.
Built on our research heritage MTIF has internationally renowned expertise in four scientific domains. Our product development capabilities can be applied to these scientific domains and many other areas of medical technology development.
Biomaterials are those materials that interact with biological systems. Biomaterials are often used in medical technologies to augment or replace a natural function. MTIF has extensive capabilities in the development, fabrication and testing of biomaterials. Our expertise and world class facilities enable partners to access a variety of approaches including electrospinning, 3D printing of composites including polymers and metals as well as solid form fabrication. We can engineer further surface modifications in the form of functional coatings to modify the release of therapeutic agents or to control cellular function. We have a variety of analytical capabilities essential in guiding successful biomaterial development including techniques to assess biological attributes, chemical composition, magnetic properties, mechanical loading, porosity, release profiles and stiffness.
Cell, Molecule and Material Interaction
Cell, Molecule and Material Interaction is an essential component in the development of the next generation therapies including Advanced Therapy Medicinal Products (ATMPs). Our capabilities cover core discovery techniques utilising both primary derived human and animal cells as well as immortalised cell lines in static and flow bioreactors. We utilise primary, terminally differentiated and progenitor cell sources to evaluate biocompatibility. MTIF is able to develop in vitro platforms such as 3D tissue analogues, enabling the development of cellular models using tissue-on-a-chip, Clustered Regularly Interspaced Short Palindromic Repeats – associated protein-9 nuclease (CRISPR/Cas9) or combinations of both approaches. We are able to fully characterise materials including testing to IS010993.
Robotics are playing an increasingly important role in health and care applications. Our capabilities enable the development of semi-autonomous robotic systems in areas as diverse as in-hospital surgical logistics and systems that assist surgeons in delicate spinal operations where accuracy is paramount. We can support the development of your companion and assistive robotic systems from early prototyping through testing in our Integrated Theatre Suite to clinical testing in our partner NHS Trusts.
Smart textiles are conventional fabrics containing integrated electronic functionality. MTIF works across three broad categories – Textiles with a sensing function referred to as passive, smart textiles, Textiles with an actuating function described as active, smart textiles, Textiles with an adaptive function called ultra-smart textiles containing a sensor, actuator and processor to tailor their output. MTIF offers two approaches to smart textile production, yarn integrated with discrete electronic components encapsulated within a textile sleeve to form a functional yarn and printed smart textiles where the electronic circuit is formed directly on the textile using functional inks.
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